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Current Research Projects

HES and NICOR data linkage for cardiac failure population analysis

Summary: This research will encompass a population-based, patient-level analysis of heart failure in England over a 5-year period using a dataset created by linking the HES and NICOR databases. Analyses will look into the re-occurrence of hospitalisation after the initial diagnosis of heart failure, the influence of population factors on risk of re-hospitalisation and the resultant cost implications.

Patient notification leaflet – Research

VICORI (Virtual Cardio-Oncology Research Initiative)

Summary: Heart disease and cancer are the commonest causes of death in the UK. Treatments are leading to better outcomes which means people are living longer with these conditions. This means more
people are living with both conditions. These conditions interact on many levels and yet there is little
current research focused on these interactions. The Virtual Cardio-Oncology Research Initiative
(VICORI) is a collaborative programme funded by the British Heart Foundation (BHF) and Cancer Research UK (CRUK) to investigate, using data collected as part of national audits, the interaction
between heart disease and cancer.

VICORI Fair Processing Statement

Use and impact of the pre-hospital 12-lead electrocardiogram in the primary PCI era. Mixed method study (PHECG-2)

Summary: When someone has a suspected heart attack the ambulance service are equipped to perform a
heart tracing to determine whether they need to take the patient to a specialist hospital
department. Our previous research showed that patients who had this test – pre hospital
electrocardiogram, or PHECG – had a better chance of survival. But a third of patients who should
have didn’t receive the test. Our previous research took place at the time when the main treatment
for heart attack was ‘clot busting’ drugs. Treatment has since changed and is now mainly with
balloons and stents. We don’t know if the PHECG is still associated with benefit in the modern era
and want to look at data from a large national heart attack audit (Myocardial Ischaemia National
Audit project or MINAP) to assess this. We also want to understand more about how ambulance
staff decide to perform the PHECG test, so plan to look at ambulance records and hold focus
group discussions with ambulance staff. Using these different types of research methods we hope
to be able to learn about barriers and facilitators to the use of the PHECG test so more patients
benefit and have better outcomes following their heart attack.

Patient notification leaflet for research

LAUNCHES QI (Linking AUdit and National datasets in Congenital HEart Services for quality improvement)

Summary: LAUNCHES QI is a research study which is funded by the charity the Health Foundation.  The chief investigators are Professor Christina Pagel and Dr Sonya Crowe, and the study sponsor is University College London (UCL).  The research study is not collecting any new data as part of the study, but using data already collected routinely across England and Wales, to understand better the quality of services that the NHS provides to people born with Congenital Heart Disease.  The National Congenital Heart Disease Audit (NHCDA) has collected information on every heart procedure performed on children and adults with congenital heart disease in the UK since 2000.  The project will use this data from English and Welsh hospitals to understand better what happened to patients in the NCHDA database (of any nationality), by looking for data on these patients that appear in four other national, routinely collected, datasets.  Services for congenital heart disease span a patient’s lifetime, but at the moment their quality is mainly measured by 30-day survival following children’s heart surgery – the project aims to create a more comprehensive and meaningful picture of services so that both services and information available to patients and their families can be continually improved.

LAUNCHES Fair Processing Statement